Eur J Endocrinol
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DOI: 10.1530/acta.0.1150084
Acta Endocrinologica, Vol 115, Issue 1, 84-86
Copyright © 1987 by European Society of Endocrinology
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Effect of sham-feeding on glucose tolerance and insulin secretion

M. Lorentzen, S. Madsbad, H. Kehlet and B. Tronier

Abstract. Glucose, 25 g, was infused iv with or without sham-feeding in seven normal males. Sham-feeding improved glucose tolerance, incremental area of blood glucose being 63% (P < 0.05) of that during iv glucose without sham-feeding. The actual insulin secretion evaluated from the total area under the C-peptide and insulin curves did not differ during iv glucose with or without sham-feeding. These results suggest that the cephalic-vagal reflex improves glucose tolerance during iv glucose, independent of changes in β-cell function.






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Copyright © 1987 European Society of Endocrinology.